Detectives searching for a Cardiff woman who has been missing since last summer have launched a murder investigation.
Three arrests have previously been made in connection with the disappearance of Charlene Hobbs.
Crimestoppers is now offering a reward of up to £20,000 for information that leads to the arrest and conviction of those responsible.
The last confirmed sighting of the 36-year-old, from Riverside, was a photograph taken on a mobile phone at a house in Broadway in the Adamsdown area of the city on 24 July last year.
Ms Hobbs, who has a distinctive dragon tattoo on her back, had her hair in a bun and was wearing a dark strapless top when the photo was taken.
The day before she was last seen, she was captured on CCTV at a Morrisons Local in Adamsdown.
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In a statement released through South Wales Police, Ms Hobbs’ family said: “We still hope that Charlene can be found safe and well.
“We are grateful for the support of Crimestoppers and the reward to help us find her, and hope that this will help people to come forward with information about what has happened to Charlene.”
Detective Chief Inspector Matt Powell said: “We have always been determined to find Charlene alive and return her to her family, but despite a huge number of enquiries we have no proof that Charlene is alive.
“While I have always maintained an open mind, the lack of evidence that Charlene is alive means that we are now treating her disappearance as a murder investigation.
“We have spoken to more than 250 people, either known to Charlene or from areas where she is known to frequent, and no one can tell us where Charlene is or that she is alive, which of course we, her family and friends desperately want to hear.
“Several of those we have spoken to believe that she has died but no one has been able to provide any specific details.”
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Detectives and specialist search teams are continuing with extensive efforts to find Ms Hobbs and determine the circumstances around her disappearance.
DCI Powell added: “I still firmly believe that answers lie in the community, and that someone out there holds key information that will help us find Charlene.”
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A 45-year-old man arrested in connection with the investigation remains on police bail.
A 43-year-old man and a 38-year-old woman have been released without charge.
